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More Than Just a Cargo Adapter, Melanophilin Prolongs and Slows Processive Runs of Myosin Va

Myosin Va (myoVa) is a molecular motor that processively transports cargo along actin tracks. One well studied cargo in vivo is the melanosome, a pigment organelle that is moved first by kinesin on microtubules and then handed off to myoVa for transport in the actin-rich dendritic periphery of melan...

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Main Authors: Sckolnick, Maria, Krementsova, Elena B., Warshaw, David M., Trybus, Kathleen M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795233/
https://ncbi.nlm.nih.gov/pubmed/23979131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476929
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