Enhanced penetration into 3D cell culture using two and three layered gold nanoparticles

Nano-scale particles sized 10–400 nm administered systemically preferentially extravasate from tumor vasculature due to the enhanced permeability and retention effect. Therapeutic success remains elusive, however, because of inhomogeneous particle distribution within tumor tissue. Insufficient tumor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: England, Christopher G, Priest, Thomas, Zhang, Guandong, Sun, Xinghua, Patel, Dhruvinkumar N, McNally, Lacey R, van Berkel, Victor, Gobin, André M, Frieboes, Hermann B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794839/
https://ncbi.nlm.nih.gov/pubmed/24124360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51668
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