Enhanced penetration into 3D cell culture using two and three layered gold nanoparticles

Nano-scale particles sized 10–400 nm administered systemically preferentially extravasate from tumor vasculature due to the enhanced permeability and retention effect. Therapeutic success remains elusive, however, because of inhomogeneous particle distribution within tumor tissue. Insufficient tumor...

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Detalhes bibliográficos
Main Authors: England, Christopher G, Priest, Thomas, Zhang, Guandong, Sun, Xinghua, Patel, Dhruvinkumar N, McNally, Lacey R, van Berkel, Victor, Gobin, André M, Frieboes, Hermann B
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794839/
https://ncbi.nlm.nih.gov/pubmed/24124360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51668
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