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Ibuprofen Rescues Abnormalities in Periodontal Tissues in Conditional Presenilin 1 and Presenilin 2 Double Knockout Mice

We used forebrain-specific conditional presenilin 1 (PS1) and presenilin 2 (PS2) double knockout mice (dKO mice) that exhibit symptoms of neurodegenerative diseases, especially Alzheimer’s disease, to investigate whether ibuprofen can rescue brain and periodontal tissue abnormalities by attenuating...

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Bibliographic Details
Main Authors: Su, Jiansheng, Gu, Jiamei, Dong, Zhuo, Mei, Bing
Format: Artigo
Language:Inglês
Published: MDPI 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794789/
https://ncbi.nlm.nih.gov/pubmed/24018889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140918457
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