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Bicistronic Gene Transfer Tools for Delivery of miRNAs and Protein Coding Sequences

MicroRNAs (miRNAs) are a category of small RNAs that modulate levels of proteins via post-transcriptional inhibition. Currently, a standard strategy to overexpress miRNAs is as mature miRNA duplexes, although this method is cumbersome if multiple miRNAs need to be delivered. Many of these miRNAs are...

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Autors principals: Stoller, Michelle L., Chang, Henry C., Fekete, Donna M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794778/
https://ncbi.nlm.nih.gov/pubmed/24013374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140918239
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