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Trifluoroethanol Modulates Amyloid Formation by the All α-Helical URN1 FF Domain

Amyloid fibril formation is implicated in different human diseases. The transition between native α-helices and nonnative intermolecular β-sheets has been suggested to be a trigger of fibrillation in different conformational diseases. The FF domain of the URN1 splicing factor (URN1-FF) is a small al...

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Detalhes bibliográficos
Main Authors: Marinelli, Patrizia, Castillo, Virginia, Ventura, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794755/
https://ncbi.nlm.nih.gov/pubmed/23999589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140917830
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