The Fold Variant BM4 Is Beneficial in a Therapeutic Bet v 1 Mouse Model

Background. Specific immunotherapy using recombinant allergens is clinically effective; still wild-type allergens can provoke treatment-induced side effects and often show poor immunogenicity in vivo. Thus, we tested the low IgE-binding, highly immunogenic fold variant BM4 in a Bet v 1 mouse model....

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Autors principals: Pichler, Ulrike, Asam, Claudia, Weiss, Richard, Isakovic, Almedina, Hauser, Michael, Briza, Peter, Ferreira, Fatima, Wallner, Michael
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794650/
https://ncbi.nlm.nih.gov/pubmed/24175303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/832404
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