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Protein–DNA binding dynamics predict transcriptional response to nutrients in archaea

Organisms across all three domains of life use gene regulatory networks (GRNs) to integrate varied stimuli into coherent transcriptional responses to environmental pressures. However, inferring GRN topology and regulatory causality remains a central challenge in systems biology. Previous work charac...

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Détails bibliographiques
Auteurs principaux: Todor, Horia, Sharma, Kriti, Pittman, Adrianne M. C., Schmid, Amy K.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794607/
https://ncbi.nlm.nih.gov/pubmed/23892291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt659
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