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Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation

DNA repair is the first barrier in the defense against genotoxic stress. In recent years, mechanisms that recognize DNA damage and activate DNA repair functions through transcriptional upregulation and post-translational modification were the focus of intensive research. Most DNA repair pathways are...

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Detalhes bibliográficos
Main Authors: Christmann, Markus, Kaina, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794595/
https://ncbi.nlm.nih.gov/pubmed/23892398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt635
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