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Elevated Expression of Fractalkine (CX3CL1) and Fractalkine Receptor (CX3CR1) in the Dorsal Root Ganglia and Spinal Cord in Experimental Autoimmune Encephalomyelitis: Implications in Multiple Sclerosis-Induced Neuropathic Pain

Multiple sclerosis (MS) is a central nervous system (CNS) disease resulting from a targeted autoimmune-mediated attack on myelin proteins in the CNS. The release of Th1 inflammatory mediators in the CNS activates macrophages, antibodies, and microglia resulting in myelin damage and the induction of...

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Détails bibliographiques
Auteurs principaux: Zhu, Wenjun, Acosta, Crystal, MacNeil, Brian, Cortes, Claudia, Intrater, Howard, Gong, Yuewen, Namaka, Mike
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794538/
https://ncbi.nlm.nih.gov/pubmed/24175290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/480702
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