The Effect of p38MAPK on Cyclic Stretch in Human Facial Hypertrophic Scar Fibroblast Differentiation

Hypertrophic scars (HTS), the excessive deposition of scar tissue by fibroblasts, is one of the most common skin disorders. Fibroblasts derived from surgical scar tissue produce high levels of α-smooth muscle actin (α-SMA) and transforming growth factor-β1 (TGF-β1). However, the molecular mechanisms...

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Main Authors: Du, Qi-cui, Zhang, Dai-zun, Chen, Xiu-juan, Lan-Sun, Gui, Wu, Min, Xiao, Wen-lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794006/
https://ncbi.nlm.nih.gov/pubmed/24130728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075635
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