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A Vaccinia Virus Recombinant Transcribing an Alphavirus Replicon and Expressing Alphavirus Structural Proteins Leads to Packaging of Alphavirus Infectious Single Cycle Particles

Poxviruses and Alphaviruses constitute two promising viral vectors that have been used extensively as expression systems, or as vehicles for vaccine purposes. Poxviruses, like vaccinia virus (VV) are well-established vaccine vectors having large insertion capacity, excellent stability, and ease of a...

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Autors principals: Sánchez-Puig, Juana M., Lorenzo, María M., Blasco, Rafael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793997/
https://ncbi.nlm.nih.gov/pubmed/24130722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075574
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