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Regression of Fibrosis and Reversal of Cirrhosis in Rats by Galectin Inhibitors in Thioacetamide-Induced Liver Disease

Galectin-3 protein is critical to the development of liver fibrosis because galectin-3 null mice have attenuated fibrosis after liver injury. Therefore, we examined the ability of novel complex carbohydrate galectin inhibitors to treat toxin-induced fibrosis and cirrhosis. Fibrosis was induced in ra...

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Detalhes bibliográficos
Main Authors: Traber, Peter G., Chou, Hsin, Zomer, Eliezer, Hong, Feng, Klyosov, Anatole, Fiel, Maria-Isabel, Friedman, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793988/
https://ncbi.nlm.nih.gov/pubmed/24130706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075361
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