Targeting Androgen Receptor/Src Complex Impairs the Aggressive Phenotype of Human Fibrosarcoma Cells

BACKGROUND: Hormones and growth factors influence the proliferation and invasiveness of human mesenchymal tumors. The highly aggressive human fibrosarcoma HT1080 cell line harbors classical androgen receptor (AR) that responds to androgens triggering cell migration in the absence of significant mito...

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Bibliografiske detaljer
Main Authors: Castoria, Gabriella, Giovannelli, Pia, Di Donato, Marzia, Hayashi, Ryo, Arra, Claudio, Appella, Ettore, Auricchio, Ferdinando, Migliaccio, Antimo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793924/
https://ncbi.nlm.nih.gov/pubmed/24130806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076899
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