Targeting Androgen Receptor/Src Complex Impairs the Aggressive Phenotype of Human Fibrosarcoma Cells

BACKGROUND: Hormones and growth factors influence the proliferation and invasiveness of human mesenchymal tumors. The highly aggressive human fibrosarcoma HT1080 cell line harbors classical androgen receptor (AR) that responds to androgens triggering cell migration in the absence of significant mito...

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Bibliographische Detailangaben
Hauptverfasser: Castoria, Gabriella, Giovannelli, Pia, Di Donato, Marzia, Hayashi, Ryo, Arra, Claudio, Appella, Ettore, Auricchio, Ferdinando, Migliaccio, Antimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793924/
https://ncbi.nlm.nih.gov/pubmed/24130806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076899
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