Targeting Androgen Receptor/Src Complex Impairs the Aggressive Phenotype of Human Fibrosarcoma Cells

BACKGROUND: Hormones and growth factors influence the proliferation and invasiveness of human mesenchymal tumors. The highly aggressive human fibrosarcoma HT1080 cell line harbors classical androgen receptor (AR) that responds to androgens triggering cell migration in the absence of significant mito...

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Détails bibliographiques
Auteurs principaux: Castoria, Gabriella, Giovannelli, Pia, Di Donato, Marzia, Hayashi, Ryo, Arra, Claudio, Appella, Ettore, Auricchio, Ferdinando, Migliaccio, Antimo
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793924/
https://ncbi.nlm.nih.gov/pubmed/24130806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076899
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