Targeting Androgen Receptor/Src Complex Impairs the Aggressive Phenotype of Human Fibrosarcoma Cells

BACKGROUND: Hormones and growth factors influence the proliferation and invasiveness of human mesenchymal tumors. The highly aggressive human fibrosarcoma HT1080 cell line harbors classical androgen receptor (AR) that responds to androgens triggering cell migration in the absence of significant mito...

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Main Authors: Castoria, Gabriella, Giovannelli, Pia, Di Donato, Marzia, Hayashi, Ryo, Arra, Claudio, Appella, Ettore, Auricchio, Ferdinando, Migliaccio, Antimo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793924/
https://ncbi.nlm.nih.gov/pubmed/24130806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076899
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