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ReaChR: A red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

Channelrhodopsins are used to optogenetically depolarize neurons. We engineered a variant of channelrhodopsin, denoted Red-activatable Channelrhodopsin (ReaChR), that is optimally excited with orange to red light (λ ~ 590 to 630 nm) and offers improved membrane trafficking, higher photocurrents, and...

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Bibliografiset tiedot
Päätekijät: Lin, John Y., Knutsen, Per Magne, Muller, Arnaud, Kleinfeld, David, Tsien, Roger Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793847/
https://ncbi.nlm.nih.gov/pubmed/23995068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3502
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