Aryl Hydrocarbon Receptor Ligands Inhibit IGF-II and Adipokine Stimulated Breast Cancer Cell Proliferation

Obesity increases human cancer risk and the risk for cancer recurrence. Adipocytes secrete paracrine factors termed adipokines that stimulate signaling in cancer cells that induce proliferation. The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that plays roles in tumori...

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Bibliografiske detaljer
Main Authors: Salisbury, Travis B., Morris, Gary Z., Tomblin, Justin K., Chaudhry, Ateeq R., Cook, Carla R., Santanam, Nalini
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793317/
https://ncbi.nlm.nih.gov/pubmed/24171117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/104850
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