Aryl Hydrocarbon Receptor Ligands Inhibit IGF-II and Adipokine Stimulated Breast Cancer Cell Proliferation

Obesity increases human cancer risk and the risk for cancer recurrence. Adipocytes secrete paracrine factors termed adipokines that stimulate signaling in cancer cells that induce proliferation. The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that plays roles in tumori...

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Detalhes bibliográficos
Main Authors: Salisbury, Travis B., Morris, Gary Z., Tomblin, Justin K., Chaudhry, Ateeq R., Cook, Carla R., Santanam, Nalini
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793317/
https://ncbi.nlm.nih.gov/pubmed/24171117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/104850
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