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Health Benefits and Cost-Effectiveness of Primary Genetic Screening for Lynch Syndrome in the General Population

In current clinical practice, genetic testing to detect Lynch syndrome mutations ideally begins with diagnostic testing of an individual affected with cancer before offering predictive testing to at-risk relatives. An alternative strategy that warrants exploration involves screening unaffected indiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dinh, Tuan A., Rosner, Benjamin I., Atwood, James C., Boland, C. Richard, Syngal, Sapna, Vasen, Hans F. A., Gruber, Stephen B., Burt, Randall W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793254/
https://ncbi.nlm.nih.gov/pubmed/21088223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0262
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