Targeting the Epigenome in Lung Cancer: Expanding Approaches to Epigenetic Therapy

Epigenetic aberrations offer dynamic and reversible targets for cancer therapy; increasingly, alteration via overexpression, mutation, or rearrangement is found in genes that control the epigenome. Such alterations suggest a fundamental role in carcinogenesis. Here, we consider three epigenetic mech...

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Autori principali: Jakopovic, Marko, Thomas, Anish, Balasubramaniam, Sanjeeve, Schrump, David, Giaccone, Giuseppe, Bates, Susan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793201/
https://ncbi.nlm.nih.gov/pubmed/24130964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00261
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