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Coval: Improving Alignment Quality and Variant Calling Accuracy for Next-Generation Sequencing Data
Accurate identification of DNA polymorphisms using next-generation sequencing technology is challenging because of a high rate of sequencing error and incorrect mapping of reads to reference genomes. Currently available short read aligners and DNA variant callers suffer from these problems. We devel...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3792961/ https://ncbi.nlm.nih.gov/pubmed/24116042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075402 |
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