Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells

Recombinant adeno-associated viral (AAV) vectors have been shown to be one of the most promising vectors for therapeutic gene delivery because they can induce efficient and long-term transduction in non-dividing cells with negligible side-effects. However, as AAV vectors mostly remain episomal, vect...

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Hlavní autoři: Zhang, Wenli, Solanki, Manish, Müther, Nadine, Ebel, Melanie, Wang, Jichang, Sun, Chuanbo, Izsvak, Zsuzsanna, Ehrhardt, Anja
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792901/
https://ncbi.nlm.nih.gov/pubmed/24116154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076771
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