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Down-Regulation of Notch-1 Is Associated With Akt and FoxM1 in Inducing Cell Growth Inhibition and Apoptosis in Prostate Cancer Cells

Although many studies have been done to uncover the mechanisms by which down-regulation of Notch-1 exerts its anti-tumor activity against a variety of human malignancies, the precise molecular mechanisms remain unclear. In the present study, we investigated the cellular consequence of Notch-1 down-r...

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Detalhes bibliográficos
Main Authors: Wang, Zhiwei, Li, Yiwei, Ahmad, Aamir, Banerjee, Sanjeev, Azmi, Asfar S., Kong, Dejuan, Wojewoda, Christine, Miele, Lucio, Sarkar, Fazlul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792569/
https://ncbi.nlm.nih.gov/pubmed/20658545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22770
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