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Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage

Double-strand break repair by recombination requires a homology search. In yeast, induced breaks move significantly more than undamaged loci. To examine whether DNA damage provokes an increase in chromatin mobility generally, we tracked undamaged loci under DNA-damaging conditions. We found that the...

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Autors principals: Seeber, Andrew, Dion, Vincent, Gasser, Susan M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792476/
https://ncbi.nlm.nih.gov/pubmed/24029917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.222992.113
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