Characterization of novel MPS1 inhibitors with preclinical anticancer activity

Monopolar spindle 1 (MPS1), a mitotic kinase that is overexpressed in several human cancers, contributes to the alignment of chromosomes to the metaphase plate as well as to the execution of the spindle assembly checkpoint (SAC). Here, we report the identification and functional characterization of...

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Detaylı Bibliyografya
Asıl Yazarlar: Jemaà, M, Galluzzi, L, Kepp, O, Senovilla, L, Brands, M, Boemer, U, Koppitz, M, Lienau, P, Prechtl, S, Schulze, V, Siemeister, G, Wengner, A M, Mumberg, D, Ziegelbauer, K, Abrieu, A, Castedo, M, Vitale, I, Kroemer, G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792427/
https://ncbi.nlm.nih.gov/pubmed/23933817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.105
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