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The Epidemiology of Leber Hereditary Optic Neuropathy in the North East of England

We performed the first population-based clinical and molecular genetic study of Leber hereditary optic neuropathy (LHON) in a population of 2,173,800 individuals in the North East of England. We identified 16 genealogically unrelated families who harbor one of the three primary mitochondrial DNA (mt...

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Bibliographische Detailangaben
Hauptverfasser: Man, P. Y. W., Griffiths, P. G., Brown, D. T., Howell, N., Turnbull, D. M., Chinnery, P. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC379226/
https://ncbi.nlm.nih.gov/pubmed/12518276
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