Mutations in CHEK2 Associated with Prostate Cancer Risk

The DNA-damage–signaling pathway has been implicated in all human cancers. However, the genetic defects and the mechanisms of this pathway in prostate carcinogenesis remain poorly understood. In this study, we analyzed CHEK2, the upstream regulator of p53 in the DNA-damage–signaling pathway, in seve...

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Hlavní autoři: Dong, Xiangyang, Wang, Liang, Taniguchi, Ken, Wang, Xianshu, Cunningham, Julie M., McDonnell, Shannon K., Qian, Chiping, Marks, Angela F., Slager, Susan L., Peterson, Brett J., Smith, David I., Cheville, John C., Blute, Michael L., Jacobsen, Steve J., Schaid, Daniel J., Tindall, Donald J., Thibodeau, Stephen N., Liu, Wanguo
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC379222/
https://ncbi.nlm.nih.gov/pubmed/12533788
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