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Matrix Metalloproteinases, New Insights into the Understanding of Neurodegenerative Disorders

Matrix metalloproteinases (MMPs) are a subfamily of zinc-dependent proteases that are responsible for degradation and remodeling of extracellular matrix proteins. The activity of MMPs is tightly regulated at several levels including cleavage of prodomain, allosteric activation, compartmentalization...

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Bibliographic Details
Main Authors: Kim, Yoon-Seong, Joh, Tong H.
Format: Artigo
Language:Inglês
Published: The Korean Society of Applied Pharmacology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792209/
https://ncbi.nlm.nih.gov/pubmed/24116286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2012.20.2.133
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