Role of Cysteines in the Stability and DNA-Binding Activity of the Hypochlorite-Specific Transcription Factor HypT

Reactive oxygen species are important components of the immune response. Hypochlorite (HOCl) is produced by neutrophils to kill invading microorganisms. The bactericidal activity of HOCl is due to proteome-wide unfolding and oxidation of proteins at cysteine and methionine residues. Escherichia coli...

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Autori principali: Drazic, Adrian, Tsoutsoulopoulos, Amelie, Peschek, Jirka, Gundlach, Jasmin, Krause, Maike, Bach, Nina C., Gebendorfer, Katharina M., Winter, Jeannette
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792123/
https://ncbi.nlm.nih.gov/pubmed/24116067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075683
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