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Mutation in the Kv3.3 Voltage-Gated Potassium Channel Causing Spinocerebellar Ataxia 13 Disrupts Sound-Localization Mechanisms

Normal sound localization requires precise comparisons of sound timing and pressure levels between the two ears. The primary localization cues are interaural time differences, ITD, and interaural level differences, ILD. Voltage-gated potassium channels, including Kv3.3, are highly expressed in the a...

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Detalhes bibliográficos
Main Authors: Middlebrooks, John C., Nick, Harry S., Subramony, S. H., Advincula, Joel, Rosales, Raymond L., Lee, Lillian V., Ashizawa, Tetsuo, Waters, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792041/
https://ncbi.nlm.nih.gov/pubmed/24116147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076749
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