Synthesis and characterization of low-toxicity N-caprinoyl-N-trimethyl chitosan as self-assembled micelles carriers for osthole

Novel amphiphilic chitosan derivatives (N-caprinoyl-N-trimethyl chitosan [CA-TMC]) were synthesized by grafting the hydrophobic moiety caprinoyl (CA) and hydrophilic moiety trimethyl chitosan to prepare carriers with good compatibility for poorly soluble drugs. Based on self-assembly, CA-TMC can for...

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Dettagli Bibliografici
Autori principali: Hu, Xiao-juan, Liu, Yang, Zhou, Xiao-feng, Zhu, Qiao-ling, Bei, Yong-yan, You, Ben-gang, Zhang, Chun-ge, Chen, Wei-liang, Wang, Zhou-li, Zhu, Ai-jun, Zhang, Xue-nong, Fan, Yu-jiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792007/
https://ncbi.nlm.nih.gov/pubmed/24106424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S46369
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