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Treatment of Recurrent Metastatic Head and Neck Cancer: Focus on Cetuximab

EGFR belongs to the ErbB family of receptor tyrosine kinases and is associated with worse prognosis in head and neck squamous cell carcinoma (HNSCC). Cetuximab is a monoclonal antibody to the extracellular domain of EGFR and inhibits its downstream actions via multiple mechanisms. Besides its proven...

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Detalhes bibliográficos
Main Authors: Patel, Akshar N., Mehnert, Janice M., Kim, Sung
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791949/
https://ncbi.nlm.nih.gov/pubmed/24179404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMENT.S5129
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