Family-Based Analysis Using a Dense Single-Nucleotide Polymorphism–Based Map Defines Genetic Variation at PSORS1, the Major Psoriasis-Susceptibility Locus

Psoriasis is a common skin disorder of multifactorial origin. Genomewide scans for disease susceptibility have repeatedly demonstrated the existence of a major locus, PSORS1 (psoriasis susceptibility 1), contained within the major histocompatibility complex (MHC), on chromosome 6p21. Subsequent refi...

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Main Authors: Veal, Colin D., Capon, Francesca, Allen, Michael H., Heath, Emma K., Evans, Julie C., Jones, Andrew, Patel, Shanta, Burden, David, Tillman, David, Barker, Jonathan N. W. N., Trembath, Richard C.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2002
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC379192/
https://ncbi.nlm.nih.gov/pubmed/12148091
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