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De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy

Denervation of skeletal muscles induces atrophy, preceded by changes in sarcolemma permeability of causes not yet completely understood. Here, we show that denervation-induced Evans blue dye uptake in vivo of fast, but not slow, myofibers was acutely inhibited by connexin (Cx) hemichannel/pannexin1...

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Main Authors: Cea, Luis A., Cisterna, Bruno A., Puebla, Carlos, Frank, Marina, Figueroa, Xavier F., Cardozo, Christopher, Willecke, Klaus, Latorre, Ramón, Sáez, Juan C.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791696/
https://ncbi.nlm.nih.gov/pubmed/24043768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312331110
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