Extensive sphingolipid depletion does not affect lipid raft integrity or lipid raft localization and efflux function of the ABC transporter MRP1

We show that highly efficient depletion of sphingolipids in two different cell lines does not abrogate the ability to isolate Lubrol-based DRMs (detergent-resistant membranes) or detergent-free lipid rafts from these cells. Compared with control, DRM/detergent-free lipid raft fractions contain equal...

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Detalhes bibliográficos
Main Authors: Klappe, Karin, Dijkhuis, Anne-Jan, Hummel, Ina, vanDam, Annie, Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Brown, H. Alex, Permentier, Hjalmar, Kok, Jan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791605/
https://ncbi.nlm.nih.gov/pubmed/20604746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091882
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