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Macrophages lift off surface-bound bacteria using a filopodium-lamellipodium hook-and-shovel mechanism

To clear pathogens from host tissues or biomaterial surfaces, phagocytes have to break the adhesive bacteria-substrate interactions. Here we analysed the mechanobiological process that enables macrophages to lift-off and phagocytose surface-bound Escherichia coli (E. coli). In this opsonin-independe...

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Detalhes bibliográficos
Main Authors: Möller, Jens, Lühmann, Tessa, Chabria, Mamta, Hall, Heike, Vogel, Viola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791455/
https://ncbi.nlm.nih.gov/pubmed/24097079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02884
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