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Gene promoters dictate histone occupancy within genes

Spt6 is a transcriptional elongation factor and histone chaperone that reassembles transcribed chromatin. Genome-wide H3 mapping showed that Spt6 preferentially maintains nucleosomes within the first 500 bases of genes and helps define nucleosome-depleted regions in 5′ and 3′ flanking sequences. In...

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Autori principali: Perales, Roberto, Erickson, Benjamin, Zhang, Lian, Kim, Hyunmin, Valiquett, Elan, Bentley, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Molecular Biology Organization 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791371/
https://ncbi.nlm.nih.gov/pubmed/24013117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.194
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