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Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor

Self-renewal of pluripotent mouse embryonic stem (ES) cells is sustained by the cytokine leukaemia inhibitory factor (LIF) acting through the transcription factor Stat3. Several targets of Stat3 have previously been identified, most notably the reprogramming factor Klf4. However, such factors are ne...

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Detalhes bibliográficos
Main Authors: Martello, Graziano, Bertone, Paul, Smith, Austin
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791366/
https://ncbi.nlm.nih.gov/pubmed/23942233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.177
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