A Phase I Study of Erlotinib and Hydroxychloroquine in Advanced Non-Small Cell Lung Cancer

INTRODUCTION: This investigator-initiated study explores the safety, maximum tolerated dose (MTD), clinical response, and pharmacokinetics (PK) of hydroxychloroquine (HCQ) with and without erlotinib in patients with advanced non-small cell lung cancer (NSCLC). METHODS: Patients with prior clinical b...

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Detalhes bibliográficos
Main Authors: Goldberg, Sarah B., Supko, Jeffrey G., Neal, Joel W., Muzikansky, Alona, Digumarthy, Subba, Fidias, Panos, Temel, Jennifer S., Heist, Rebecca S., Shaw, Alice T., McCarthy, Patricia O., Lynch, Thomas J., Sharma, Sreenath, Settleman, Jeffrey E., Sequist, Lecia V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791327/
https://ncbi.nlm.nih.gov/pubmed/22878749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318262de4a
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