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Formation of Chimeric Genes by Copy-Number Variation as a Mutational Mechanism in Schizophrenia

Chimeric genes can be caused by structural genomic rearrangements that fuse together portions of two different genes to create a novel gene. We hypothesize that brain-expressed chimeras may contribute to schizophrenia. Individuals with schizophrenia and control individuals were screened genome wide...

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Autors principals: Rippey, Caitlin, Walsh, Tom, Gulsuner, Suleyman, Brodsky, Matt, Nord, Alex S., Gasperini, Molly, Pierce, Sarah, Spurrell, Cailyn, Coe, Bradley P., Krumm, Niklas, Lee, Ming K., Sebat, Jonathan, McClellan, Jon M., King, Mary-Claire
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791253/
https://ncbi.nlm.nih.gov/pubmed/24094746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.09.004
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