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A Rheostat Model for a Rapid and Reversible Form of Imprinting-Dependent Evolution
The evolutionary advantages of genomic imprinting are puzzling. We propose that genomic imprinting evolved as a mechanism that maximizes the interindividual variability in the rates of gene expression for dosage-sensitive loci that, with minimal unrelated deleterious effects, can alter the phenotype...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Human Genetics
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC379123/ https://ncbi.nlm.nih.gov/pubmed/11992247 |
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