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Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis

Nonalcoholic fatty liver disease is the most common liver disease in both adults and children. The earliest stage of this disease is hepatic steatosis, in which triglycerides are deposited as cytoplasmic lipid droplets in hepatocytes. Through a forward genetic approach in zebrafish, we found that gu...

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Detalhes bibliográficos
Main Authors: Nussbaum, Justin M., Liu, Liuhong J., Hasan, Syeda A., Schaub, Madeline, McClendon, Allyson, Stainier, Didier Y.R., Sakaguchi, Takuya F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791216/
https://ncbi.nlm.nih.gov/pubmed/23744565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26551
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