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Visualization of Peroxynitrite-Induced Changes of Labile Zn(2+) in the Endoplasmic Reticulum with Benzoresorufin-based Fluorescent Probes

Zn(2+) plays essential roles in biology, and the homeostasis of Zn(2+) is tightly regulated in all cells. Subcellular distribution and trafficking of labile Zn(2+), and its interrelation with reactive nitrogen species, are poorly understood due to the scarcity of appropriate imaging tools. We report...

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Main Authors: Lin, Wei, Buccella, Daniela, Lippard, Stephen J.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791137/
https://ncbi.nlm.nih.gov/pubmed/23902285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4059487
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