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Ustekinumab in the treatment of psoriatic arthritis: latest findings and clinical potential
Ustekinumab (UST) is a fully human immunoglobulin G1κ (IgG1κ) monoclonal antibody against common sub-unit p40 of interleukin-12 (IL-12) and interleukin-23 (IL-23). IL-12 and IL-23 are essential components of the Th1 and Th17 inflammatory pathways, respectively, and are the key mediators of psoriasis...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publications
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791091/ https://ncbi.nlm.nih.gov/pubmed/24101949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X13501021 |
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