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Evolutionary Fate of an Unstable Human Minisatellite Deduced from Sperm-Mutation Spectra of Individual Alleles

Although mutation processes at some human minisatellites have been extensively characterized, the evolutionary fate of these unstable loci is unknown. Minisatellite instability is largely germline specific, with mutation rates up to several percent and with expansion events predominating over contra...

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Bibliographic Details
Main Authors: Buard, Jérôme, Brenner, Charles, Jeffreys, Alec J.
Format: Artigo
Language:Inglês
Published: The American Society of Human Genetics 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC379099/
https://ncbi.nlm.nih.gov/pubmed/11859482
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