Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation

The contributions of vasoconstrictors (endothelin-1 (ET-1), peroxynitrite) and endothelium-dependent vasodilatory mechanisms to basal tone were investigated in parenchymal arterioles (PAs) after early postischemic reperfusion. Transient middle cerebral artery occlusion (tMCAO) was induced for 2 hour...

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Autori principali: Cipolla, Marilyn J, Sweet, Julie G, Gokina, Natalia I, White, Sheryl L, Nelson, Mark T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Feature Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790940/
https://ncbi.nlm.nih.gov/pubmed/23778163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.99
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