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Posttraumatic reduction of edema with aquaporin-4 RNA interference improves acute and chronic functional recovery

Traumatic brain injury (TBI) is common in young children and adolescents and is associated with long-term disability and mortality. The neuropathologic sequelae that result from juvenile TBI are a complex cascade of events that include edema formation and brain swelling. Brain aquaporin-4 (AQP4) has...

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Detalhes bibliográficos
Main Authors: Fukuda, Andrew M, Adami, Arash, Pop, Viorela, Bellone, John A, Coats, Jacqueline S, Hartman, Richard E, Ashwal, Stephen, Obenaus, Andre, Badaut, Jerome
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790933/
https://ncbi.nlm.nih.gov/pubmed/23899928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.118
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