Inhibition of soluble epoxide hydrolase after cardiac arrest/cardiopulmonary resuscitation induces a neuroprotective phenotype in activated microglia and improves neuronal survival

Cardiac arrest (CA) causes hippocampal neuronal death that frequently leads to severe loss of memory function in survivors. No specific treatment is available to reduce neuronal death and improve functional outcome. The brain's inflammatory response to ischemia can exacerbate injury and provide...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Jianming, Fujiyoshi, Tetsuhiro, Kosaka, Yasuharu, Raybuck, Jonathan D, Lattal, K Matthew, Ikeda, Mizuko, Herson, Paco S, Koerner, Ines P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790926/
https://ncbi.nlm.nih.gov/pubmed/23820647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.111
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