Loading...

Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Gba1 Mutant Mouse Model Treated with Velaglucerase alfa or Imiglucerase

Gaucher disease type 1, an inherited lysosomal storage disorder, is caused by mutations in GBA1 leading to defective glucocerebrosidase (GCase) function and consequent excess accumulation of glucosylceramide/glucosylsphingosine in visceral organs. Enzyme replacement therapy (ERT) with the biosimilar...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Dasgupta, Nupur, Xu, You-Hai, Oh, Sunghee, Sun, Ying, Jia, Li, Keddache, Mehdi, Grabowski, Gregory A
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790783/
https://ncbi.nlm.nih.gov/pubmed/24124461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074912
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!