Leucine and HMB Differentially Modulate Proteasome System in Skeletal Muscle under Different Sarcopenic Conditions

In the present study we have compared the effects of leucine supplementation and its metabolite β-hydroxy-β-methyl butyrate (HMB) on the ubiquitin-proteasome system and the PI3K/Akt pathway during two distinct atrophic conditions, hindlimb immobilization and dexamethasone treatment. Leucine suppleme...

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Autori principali: Baptista, Igor L., Silva, Willian J., Artioli, Guilherme G., Guilherme, Joao Paulo L. F., Leal, Marcelo L., Aoki, Marcelo S., Miyabara, Elen H., Moriscot, Anselmo S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790739/
https://ncbi.nlm.nih.gov/pubmed/24124592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076752
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