GSTT1 Copy Number Gain and ZNF Overexpression Are Predictors of Poor Response to Imatinib in Gastrointestinal Stromal Tumors

Oncogenic mutations in gastrointestinal stromal tumors (GISTs) predict prognosis and therapeutic responses to imatinib. In wild-type GISTs, the tumor-initiating events are still unknown, and wild-type GISTs are resistant to imatinib therapy. We performed an association study between copy number alte...

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Detalhes bibliográficos
Main Authors: Lee, Eui Jin, Kang, Guhyun, Kang, Shin Woo, Jang, Kee-Taek, Lee, Jeeyun, Park, Joon Oh, Park, Cheol Keun, Sohn, Tae Sung, Kim, Sung, Kim, Kyoung-Mee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790698/
https://ncbi.nlm.nih.gov/pubmed/24124608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077219
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